In the countryside in northern Uganda, armed with petri dishes, cardboard cups and a vacuum cleaner, internationally renowned malaria researcher Teun Bousema, along with PhD student Daniel Ayo and his team, seeks to unravel the mysterious life cycle of the malaria parasite. But the parasite is elusive, constantly mutating, which increases the threat of drug resistance. Is this mutated parasite more infectious to mosquitoes? Interplay depicts the daily reality of the tireless scientific battle against this formidable and multifaceted opponent.

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The malaria mosquito is born ‘clean’. Only after an infected blood meal and taking on various forms does the malaria parasite end up in the mosquito’s saliva, ready to claim a new human victim when the mosquito next bites. ‘It’s such a clever beast,’ says Bousema.